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KMID : 0614020080230010047
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Journal of Pharmaceutical Sciences (C.N.U.)
2008 Volume.23 No. 1 p.47 ~ p.52
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Lymphoblastogenic Effect of Protein-polysaccharide Fractions of Korean Wild Mushrooms Including Russula alboareolata
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Chung Kyeong-Soo
Seok Jee-Eun
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Abstract
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As an investigation to develop novel antitumor immunotherapeutic agents, four protein-poly-saccharide fractions from Korean wild mushrooms were subjected to a flow cytometric analysis for their in vitro lymphoblastogenic activities on the BALB/c mouse splenic lymphocytes. Of these, the protein-poly-saccharide fractions of Russula alboareolata, Russula compacta and Laccaria amethystea not only showed lymphoblastogenic activity, but also increased the viability of the lymphocytes, while that of Russula nitrata exerted marked cytocidal activity.
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KEYWORD
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basidiomycete, protein-polysaccharide, Russula alboareolata, Laccaria amethystea, Russula nitrata, lymphoblastogenic activity
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